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Inhibition of β-oxidation with etomoxir, in combination with the administration of a HIF-1alpha inhibitor, compromised the tolerogenic transcriptional signature of these cells, diminishing production of the regulatory cytokines IL-10 and IL-27 ( Dendritic cells are amongst a subset of cells known as mononuclear phagocytes (MPs), which play a vital role in the host immune defenses against cancer
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No differences were detected between groups in the remaining hippocampal areas and all other analyzed ROIs, such as cortical areas, subiculum, IC, and PvWM at P5 or P9 (Extended Data Fig
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