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Neurons pretreated with Dihexa demonstrate significantly enhanced survival when exposed to reactive oxygen species, excitotoxic glutamate concentrations, or metabolic impairment compared to untreated controls
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Based on the published structure (Song et al., 2016), we suggest a possible hydrogen bonding between His192 and Asp286 with PMP due to their local proximity of a distance of 2.7 Å ( Figure 7D )
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