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It also stimulates the release of pro-inflammatory cytokines, such as IL-6 and TNF-ฮฑ, and may synergize with circulating LPS to exacerbate systemic inflammation
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The alterations described above impaired T-lymphocyte-mediated immune response, leading to a defect in the production of immune components such as IL-17, IL-22 (essential for mucosal antifungal defense) and IFN-ฮณ (essential for tumor surveillance)
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